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题目：Nonlinear Dynamics in Tumor and Immune System Interaction Models

报告人：阮士贵教授  （美国迈阿密大学）

摘要：One of the most important and challenging questions in immunology and cancer research is to understand how the immune system affects cancer development and progression. On one hand recent data on both mice and humans with cancer suggest that innate and adaptive immune cell types, effector molecules, and pathways can suppress tumor growth by destroying cancer cells or inhibiting their outgrowth. On the other hand, the immune system can also promote tumor progression either by selecting tumor cells that are more fit to survive in an immunocompetent host or by establishing conditions within the tumor microenvironment that facilitate tumor outgrowth. These dual host-protective and tumor-promoting actions of immunity make the study of tumor/immune system interactions difficult, challenging and interesting. The purpose of this talk is to introduce some simple tumor/immune system interaction models and present results on the nonlinear dynamics of such models.

报告人简介：阮士贵，美国迈阿密大学(University of Miami)数学系终身教授。主要研究领域是动力系统和微分方程及其在生物和医学中的应用。在非线性发展方程、非局部扩散方程、带年龄结构模型、生物系统的多参数分支等方向作了很多重要工作。在包括《PNAS》、《Lancet Infect Dis》、《Memoirs Amer Math Soc》、《J Math Pures Appl》、《Math Ann》等学术期刊发表了200多篇学术论文，收到了国内外同行的关注与大量引用，2014和2015年连续被汤森路透集团列为全球高被引科学家。担任了一些重要学术期刊如《BMC Infectious Diseases》、《Bulletin of Mathematical Biology》（高级编委）、《Mathematical Biosciences》等的编委。作为项目负责人多次获得美国国家卫生研究院（NIH）、美国国家科学基金（NSF）和中国国家自然科学基金多项资助。2013年获得海外及港澳学者合作研究基金（原海外杰青）资助。

报告时间：2025年5月12日（周一）上午15:30-17:00

报告地点：教二楼727

联系人：邹兰，许文兵